Gastrointestinal problems — including constipation, feeding difficulties, reflux, and motility issues — are among the most common and disruptive challenges families of children with ASXL-related disorders face. Dr. Alejandro Velez Lopez, a pediatric gastroenterologist and director of the neurogastroenterology and motility program at the University of Michigan Mott Children’s Hospital, breaks down why GI and motility challenges are so prevalent in children with neurogenetic conditions, how clinicians approach evaluation and diagnosis, and what families should know about current management strategies and treatment options.
This recording is from the 2026 ASXL Family Conference, June 26-28, Ann Arbor, Michigan, U.S.A.
Published: June 2026
The information presented here is for educational purposes only. This information is not medical advice and should not be treated as such. You should always talk to your or your family member’s health care professionals for diagnosis and treatment, including information regarding which drugs or treatment may be appropriate for you or your family member. We do not represent or warrant that any particular treatment is safe, appropriate or effective for you or your family member. In the event of a medical emergency, you should contact your doctor immediately or call your local emergency service.
