ARRE Foundation

Research funding

We fund research through a combination of open calls for research proposals that meet our strategic priorities and directed grants to support projects to fill strategic gaps in research.

Key Areas

The ARRE Foundation strategically funds research that paves the way for targeted treatments and high-quality, standardized care. Our three key areas of investment include:

  • Clinical research: We fund studies that define how ASXL-related disorders appear and progress over time – critical groundwork for designing clinical trials and developing future care guidelines.
  • Basic and translational science: We support research that explores the underlying biology of ASXL genes to uncover therapeutic targets and inform the development of disease-modifying treatments.
  • Research infrastructure and capacity: We invest in tools, networks, and data resources that expand the global ASXL research community and accelerate collaborative progress.

Funding opportunities

Call for applications: Next Generation Research Grant in ASXL-Related Neurodevelopmental Disorders
The ARRE Foundation, in partnership with the American Brain Foundation, is proud to announce the Next Generation Research Grant in ASXL-Related Neurodevelopmental Disorders focused specifically on ASXL gene function and disease mechanisms. The award will be $120,000 USD for 2 years. International and US-based academic faculty within the first 5 years of their first faculty appointment are eligible to apply. The full request for applications (PDF) is available and applications may be submitted via the ABF’s online grant portal. Applications are due by Thursday, July 30, 2026 by 5pm U.S. Central Time.

We may consider proposals outside of a call for applications that are exceptional and support our strategic priorities. If you have a project that you believe warrants consideration, please contact Karen Ho, PhD.

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ARRE Foundation policy for supporting indirect or overhead expenses

As a steward of funds raised by families affected by ASXL-related disorders, no ARRE Foundation funds may be used to support indirect costs/overhead expenses. Acceptance of ARRE Foundation funds is contingent upon the recipient and their institution complying with this policy.

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